968-24 Genetic Modification of Atherosclerotic Arteries Following Balloon Angioplasty
نویسندگان
چکیده
منابع مشابه
Effectiveness of recombinant desulphatohirudin in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits.
BACKGROUND The effectiveness of balloon angioplasty is limited by a restenosis rate of approximately 30%. Recombinant desulphatohirudin (r-hirudin [CGP 39393]) has been found to be highly effective in preventing acute platelet-rich thrombosis after deep arterial injury as compared with heparin. METHODS AND RESULTS This study evaluated the effect of intravenous r-hirudin, a selective inhibitor...
متن کاملIncidence of intimal proliferation and apoptosis following balloon angioplasty in an atherosclerotic rabbit model.
OBJECTIVE The aim of this study was to determine the occurrence of apoptosis in relation to the proliferative response in the intimal layer after experimental balloon angioplasty of a pre-existing plaque. METHODS After induction of an intimal plaque in the right carotid artery by electrical stimulation, 26 rabbits underwent balloon angioplasty. Twelve animals served as a control group without...
متن کاملPercutaneous angioplasty of atherosclerotic and postsurgical stenosis of carotid arteries.
A technique for safe angioplasty of atherosclerotic stenosis of internal and common carotid arteries is described in which temporary balloon occlusion of the internal carotid artery is used to prevent cerebral embolization during manifestation of ulcerated plaques. Its successful use in six atherosclerotic stenosis is described. Five angioplasties of postsurgical stenoses are also reported in w...
متن کاملRenal artery stenting following unsuccessful balloon angioplasty.
1. DeMaria AN. Editors page: international cardiology. J Am Coll Cardiol 2005;46:1580–1. 2. Cheng TO. The current state of cardiology in China. Int J Cardiol 2004;96:425–39. 3. Cheng TO. Metabolic syndrome in China. Circulation 2004;109:e180. 4. Cheng TO. The metabolic syndrome, formerly called metabolic ‘syndrome X.’ Am J Cardiol 2004;94:148–9. 5. Cheng TO. Obesity is the newest health risk in...
متن کاملRegulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries.
Injury to atherosclerotic arteries induces the expression of growth regulatory genes that stimulate cellular proliferation and intimal formation. Intimal expansion has been reduced in vivo in nonatherosclerotic balloon-injured arteries by transfer of genes that inhibit cell proliferation. It is not known, however, whether vascular cell proliferation can be inhibited after injury in more extensi...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1995
ISSN: 0735-1097
DOI: 10.1016/0735-1097(95)92458-h